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Graft-versus-tumor effect
Graft-versus-tumor effect (GvT) appears after allogeneic hematopoietic stem cell transplantation (HSCT). The graft contains donor T cells (T lymphocytes)
Graft-versus-host disease
to separate the undesirable graft-vs-host-disease aspects of T-cell physiology from the desirable graft-versus-tumor effect. This type of GvHD is associated
Hematopoietic stem cell transplantation
[citation needed] Graft-versus-tumor effect (GVT) or "graft versus leukemia" effect is the beneficial aspect of the Graft-versus-Host phenomenon. For example
Transplant rejection
cells Graft-versus-host disease Graft-versus-tumor effect Immunosuppression Frohn, C; Fricke, L; Puchta, JC; Kirchner, H (Feb 2001). "The effect of HLA-C
GVT
a Brazilian television channel Glyn Valley Tramway in Wales Graft-versus-tumor effect Grand Valley Trail, in Ontario, Canada Grand Valley Transit, a
Donor lymphocyte infusion
called the graft-versus-tumor effect (GVT). The donor T-cells can attack and control the growth of residual cancer cells providing the GVT effect. It is hoped
Minor histocompatibility antigen
selectively on leukemic cells in order to destroy these tumor cells referred to as graft-versus- leukemia effect (GVL). The recognition of a mature T cell to this
Treatment of cancer
the donor's immune cells will often attack the tumor in a phenomenon known as graft-versus-tumor effect. For this reason, allogeneic HSCT leads to a higher
Bone grafting
trauma or malignant tumor invasion. The periosteum and nutrient artery are generally removed with the piece of bone so that the graft will remain alive
T-cell depletion
immune system of the transplanted individual and a decreased Graft-versus-tumor effect. This problem is partially answered by more selective depletion