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April 2020
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Domain of unknown function
A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database
Domain of a function
mathematics, the domain of definition (or simply the domain) of a function is the set of all "input" or argument values for which the function is defined.
DUF
(DUF) program (now Arrestee Drug Abuse Monitoring) Domain of unknown function, a protein domain that has no characterised function Duff (disambiguation)
Protein domain
protein domain is a conserved part of a given protein sequence and tertiary structure that can evolve, function, and exist independently of the rest of the
Pfam
determined, the function of the entire DUF is updated and the family is renamed. Some named families are still domains of unknown function, that are named
RNA of unknown function
biological function has yet to be determined. The same convention is used for proteins, they can be named domains of unknown function (DUFs). Examples of RUFs
Severe acute respiratory syndrome-related coronavirus
ribosomes of its initial two large overlapping open reading frames (ORFs), 1a and 1b, both of which produce polyproteins. The functions of several of the viral
Codomain
is the set of first components of the pairs in F (the domain). The set F is called the graph of the function. The set of all elements of the form f(x)
Uncharacterized LOC644249 gene
superfamily, pfam 12001. In particular, this conserved domain contains the domain of unknown function DUF3496 which is about 110 amino acids long, functionally
FAM167A
containing the conserved domain DUF3259, a protein of unknown function. FAM167A has many orthologs in which the domain of unknown function is highly conserved